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Accutane
isotretinoin (eye-soe-TRET-i-noyn)
Accutane - Learn More


Brand Name: Accutane
(Also marketed outside the US as Roaccutane)

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Accutane Acne Medication Treatment Drug Information

Accutane is in a class of drugs called retinoids. Accutane is used to treat severe acne that has not responded to oral or topical anti-infectives.

Accutane should not be prescribed for other uses; ask your doctor or pharmacist for more information.

How should Accutane be used to treat acne?

Accutane comes as a capsule to take by mouth. Accutane usually is taken twice a day. Take Accutane with food or milk. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Accutane exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

You may not notice any improvement in your condition until after 4-6 weeks of treatment, and your acne may actually get worse during the first few weeks. Your acne should improve within 15-20 weeks. If it does not improve, your doctor will probably stop giving you Accutane for 8 weeks and then restart your treatment.

Other uses for Accutane besides for acne

Accutane has been used to treat other skin disorders, including keratosis follicularis, pityriasis rubra pilaris, lamellar ichthyosis, keratosis palmaris et plantaris, rosacea, and leukoplakia. Talk to your doctor about the possible risks of using this drug for your condition.

What special precautions should I follow when using Accutane?

Before taking Accutane
  • tell your doctor and pharmacist if you are allergic to Accutane, parabens, or any other drugs.
  • tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially carbamazepine (Tegretol), demeclocycline (Declomycin), doxycyline (Monodox, Vibramycin, and others), minocycline (Minocin), oxytetracycline (Uri-Tet), tetracycline (Achromycin V), vitamin A, and other vitamins and herbal products. Do not take any vitamin supplements that contain vitamin A to avoid possible harmful reactions.
  • tell your doctor if you have or have ever had diabetes, liver disease, pancreatitis, a high amount of triglycerides (fats) in your blood, a family history of high triglycerides in the blood, or depression.
  • plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen. Accutane may make your skin sensitive to sunlight.
  • Accutane may cause intracranial hypertension, especially when it is taken with tetracycline. Intracranial hypertension is a condition caused when the pressure in the blood vessels of the brain increases or when the brain swells. Symptoms of intracranial hypertenstion include severe headache, upset stomach and vomiting, and changes in vision. If you have any of these symptoms, call your doctor immediately.
  • be aware that this medicine may affect your night vision. Be cautious when driving or operating any machinery after dark.
  • hair removal by waxing and laser procedures to the skin should be avoided while taking Accutane and for 6 months after stopping Accutane, with it's main ingredient Isotretinoin. These procedures may cause scarring.

What special dietary instructions should I follow when taking Accutane?

Accutane increases the amount of triglycerides (fats) in your blood. Limit your intake of dietary fat and alcoholic beverages (alcohol also increases the amount of triglycerides in your blood) while taking Accutane, with it's main ingredient Isotretinoin.

What should I do if I forget a dose of Accutane?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can Accutane acne medicine cause?

Side effects from Accutane are common.Tell your doctor if any of these symptoms are severe or do not go away:
  • red, cracked, and sore lips
  • red, itchy, dry, and inflamed eyes
  • dry mouth and nose
  • dry skin
  • thinning of the hair
  • fatigue
If you experience any of the following symptoms or those listed in the IMPORTANT WARNING section, call your doctor immediately:
  • bone or joint pain
  • chest pain
  • dizziness
  • stomach pain
  • headache
  • upset stomach
  • vomiting
  • difficulty with vision
  • difficulty breathing or swallowing
  • difficulty hearing
  • ringing in your ears
  • difficulty walking
  • rectal bleeding
  • severe diarrhea
  • bruising or red patches of the skin
  • muscle aches
  • difficulty walking
  • skin peeling
  • skin infections
  • depression
  • seeing visions or hearing voices that do not exist
  • thoughts of suicide

What storage conditions are needed for Accutane?

Keep Accutane in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.


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